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Compounded in OviedoDiethylstilbestrol (DES) capsule

Medication library / Diethylstilbestrol (DES)

Kidney and urinary

Diethylstilbestrol (DES)

For petsLast updated 10/1/26
Available as
CapsuleChewable treat
Flavors
ChickenTunaBeefGrilled SalmonDuckBaconPeanut ButterMarshmallowCatnip
Start with a prescriptionVeterinarians: how to send it

Pick up in Oviedo or ship within Florida. Most compounds ready same day to 24 hours.

  • Made to your prescription. Prepared in the strength your veterinarian orders.
  • 2 dosage forms. Capsule, Chewable treat.
  • Flavor options. Chicken, Tuna, Beef, Grilled Salmon, Duck and more.
  • Pharmacist access. Call and a person answers.
Made in our pharmacyPrescription required
What is Diethylstilbestrol?

A synthetic estrogen that strengthens the urethral sphincter in spayed female dogs.

Why is it compounded?

DES is no longer commercially available, so veterinarians rely on compounding for low-dose capsules and treats.

Compounded medications are prepared from a valid prescription for an individual patient and are not FDA-approved. This page is for education and is not medical advice.

Getting your prescription filled is simple

  1. Send us the prescriptionYour veterinarian e-prescribes, faxes or calls it in to Pharmacy on the Park.
  2. A pharmacist reviews itWe verify it, confirm the price and timing, and call you.
  3. We compound it for youPick up in Oviedo or we ship within Florida.

What is Diethylstilbestrol (DES)?

Estrogen-responsive urinary incontinence in spayed female dogs.

At Pharmacy on the Park, Diethylstilbestrol is compounded in our pharmacy from a prescription, in the strength and form your veterinarian orders.

Compounded medications are not FDA-approved. They are prepared for one patient from a valid prescription. Any use may be off-label, and your veterinarian decides whether it is right for your pet.

How does it work?

A synthetic estrogen that strengthens the urethral sphincter in spayed female dogs.

What is it used for?

Estrogen-responsive urinary incontinence in spayed female dogs. Your veterinarian determines the use, dose and monitoring.

How is it used?

  • Capsule. Capsules are swallowed by mouth. For pets, a capsule can often be hidden in a small treat if your veterinarian agrees.
  • Chewable treat. Chewable treats are given like a snack.

Follow the directions on your label. The strength, amount and schedule are set by your veterinarian.

Side effects and safety

Commonly reported: Bone marrow effects at high doses; requires monitoring. Call your veterinarian or us about any reaction that concerns you.

Who should use caution?

Intact female dogs and cats. Doses are kept low and infrequent because high doses can suppress bone marrow. Share your full medical history and medication list with your veterinarian.

How should it be stored?

Keep treats sealed and follow the label; some are refrigerated. Always follow the storage directions and beyond-use date on your label, and keep medications out of reach of children and pets.

Why is it compounded?

DES is no longer commercially available, so veterinarians rely on compounding for low-dose capsules and treats.

Personalized compounding from a pharmacy that knows your name.

“The pharmacy world needs people who are fair, and I want to be as fair to as many people as possible.”

Ian Tasman, PharmD
Owner and pharmacist, Pharmacy on the Park

IT
Quality and testing

Held to a higher standard

  • AccreditedBy The Compliance Team.
  • USP <800> compliantSafe handling of hazardous drugs.
  • Meets USP <795>Nonsterile compounding standards.
  • Meets USP <797>Every sterile batch tested by Pharmetric Labs.
Our quality standards

Our formulations

Diethylstilbestrol is compounded to the strength your veterinarian orders. These are the forms we have prepared.

FormFlavorsNotes
Capsule—Capsules are swallowed by mouth
Chewable treatChicken, Tuna, Beef, Grilled Salmon, Duck, Bacon, Peanut Butter, Marshmallow, CatnipChewable treats are given like a snack

Forms are listed for education only. A valid prescription is required, and your veterinarian chooses the form, strength and schedule. Compounded medications are not FDA-approved.

For veterinarians

How to e-prescribe Diethylstilbestrol

Compounded preparations have no NDC, so they won’t appear in a standard drug search. Use your system’s compound or free-text entry.

  1. Find Pharmacy on the Park in your pharmacy directory

    Search by NCPDP or by name and ZIP. Save us as a favorite.

    NCPDP 5747239NPI 1720664709784 S Central Ave, Oviedo, FL 32765Phone 407-977-9779Fax 407-977-0079
  2. Choose the preparation
    Diethylstilbestrol capsuleDiethylstilbestrol chewable treat
    Rx: Diethylstilbestrol ___ (capsule)
Quantity: ___
Sig: ___
Refills: ___
Pharmacy: Pharmacy on the Park, 784 S Central Ave, Oviedo, FL 32765 · NCPDP 5747239 · Fax 407-977-0079
  3. Enter it as a compound

    Use compound, non-formulary or free-text entry and paste the details into the prescription body. Include strength, form, directions, quantity, species, weight and flavor if needed.

  4. Send it

    Transmit from your EHR, fax it to 407-977-0079, or call 407-977-9779 to speak with a pharmacist. We’ll call the owner when it’s received.

Put the formula in the prescription itself, not in “Notes to pharmacy.” Some systems don’t transmit that field.

Frequently asked questions

What is Diethylstilbestrol?

A synthetic estrogen that strengthens the urethral sphincter in spayed female dogs.

What is it used for?

Estrogen-responsive urinary incontinence in spayed female dogs.

What forms and flavors are available?

We have prepared it as capsule, chewable treat. Flavors include Chicken, Tuna, Beef, Grilled Salmon, Duck, Bacon, Peanut Butter, Marshmallow, Catnip.

What are the common side effects?

Bone marrow effects at high doses; requires monitoring.

Who should use caution?

Intact female dogs and cats. Doses are kept low and infrequent because high doses can suppress bone marrow.

Are compounded medications FDA-approved?

No. Compounded medications are prepared for an individual patient from a prescription and are not FDA-approved.

Do I need a prescription?

Yes. Your veterinarian sends the prescription to us and decides the strength and schedule.

Can you fill a prescription from my own veterinarian?

Yes. Ask them to e-prescribe to Pharmacy on the Park (NCPDP 5747239), fax 407-977-0079 or call 407-977-9779.

Do you ship?

Yes, within Florida. You can also pick up at 784 S. Central Ave in Oviedo.

What is compounding?

Preparing a medication for one patient from a prescription when a commercial product isn’t the right strength, form or flavor.

Pickup and shipping

OptionWhereTiming
Pickup784 S. Central Ave, OviedoMost compounds same day to 24 hours
ShippingWithin FloridaWe confirm timing when your prescription arrives

Questions? Call 407-977-9779. A person will answer.

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References

  1. DailyMed (U.S. National Library of Medicine): drug labels for Diethylstilbestrol
  2. PubMed: published studies on Diethylstilbestrol
  3. FDA: human drug compounding

General information about Diethylstilbestrol as an active ingredient, pending pharmacist review. Last updated 10/1/26. Pharmacy on the Park does not decide whether a medication is right for you; your veterinarian makes that call.

Call us. A person will answer.

Tell us what you need and we'll help you get it handled, whether it's a transfer, a compound or a question for your pharmacist.

Call 407-977-9779Send a Prescription